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BEGIN:VEVENT
DTSTAMP:20260724T034125Z
DTSTART;VALUE=DATE-TIME:20260624T131500
DTEND;VALUE=DATE-TIME:20260624T141500
SUMMARY:BMS Seminar: The 3 Rs of epigenetic inheritance: Reading\, Writin
 g and Remodeling\, Dr Kaushik Ragunathan\, Associate Professor\, Departm
 ent of Biology\, Brandeis University
TZID:Europe/London
UID:20260624-8ac672c49eab7b17019eb69ffbe676d0@warwick.ac.uk
CREATED:20260616T104231Z
DESCRIPTION:Abstract: The goal of my program of research is to define how
  dynamic and transient interactions involving chromatin modifying enzyme
 s establish stable and heritable epigenetic states. My research tackles 
 this enigma using a unique permutation of genetic\, biochemical\, and bi
 ophysical approaches that bridges our understanding of epigenetic phenom
 ena across different biological timescales. Using fission yeast (Schizos
 accharomyces pombe) as a model\, my research has advanced our understand
 ing of how silent chromatin states characterized by histone H3 lysine 9 
 methylation (H3K9me) are established\, maintained\, and remodeled on-dem
 and during adaptation.In this talk\, I will highlight the tension betwee
 n positive feedback loops that propagate epigenetic states and the sourc
 es of noise that opposes this process. By integrating experiments and th
 eory\, my talk will demonstrate how simple considerations of biophysical
  and biochemical principles can give us a comprehensive understanding of
  complex cellular processes. Biography: Kaushik Ragunathan is an Associa
 te Professor in the Department of Biology at Brandeis University\, where
  his lab studies how epigenetic states are established\, maintained\, an
 d inherited across generations\, using fission yeast as a model. Prior t
 o this\, he was a faculty member in the Department of Biological Chemist
 ry at the University of Michigan. His interdisciplinary training stems f
 rom his time as a graduate student working on single-molecule fluorescen
 ce microscopy\, before transitioning to a postdoc studying epigenetics i
 n fission yeast. Kaushik has received an American Cancer Society Researc
 h Scholar Award and an NSF CAREER Award.
LOCATION:IBRB Lecture Theatre
CATEGORIES:BiomedicalSciences,Directorate Seminars
LAST-MODIFIED:20260616T104231Z
ORGANIZER;CN=Jas Bains:
END:VEVENT
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